Bob Dotterer, Applications Engineer for Caron Products and an expert in photostability chambers, is featured in the December 2004 issue of Pharmaceutical Technology, one of the industry's leading trade publications.

The article, by contributing editor Kaylynn Chiarello, discusses how researchers are advancing the field of photodynamic therapy with effective drugs, new light sources and improved drug delivery techniques for deep tissue penetration, site specific treatment and reduced side effects. Critical to the research are photostability chambers such as those designed and manufactured by Caron.

According to Chiarello, manufacturers of photostability chambers have made strides in controlling light uniformity within the controlled environment cabinet where testing and storage protocols are performed.

In commenting for the article, Dotterer cites the need for more sophisticated control and performance from the photostability chamber. "Gone are the days of building a light box, inserting a light and saying 'I'm doing my test now'", say's Dotterer. "We've recognized that there are a lot of factors that must be controlled. Uniformity of light, humidity and temperature are very important tools. This need has created a migration to higher quality products.”

Caron has developed a complete line of photostability chambers that can be programmed to run for certain exposure levels in physical units that are consistent with guidelines established by the International Conference on Harmonization. This program feature replaces the need for a chemical actinometric system, and is superior to timers.